Process for increasing the efficiency of magnetic iron oxide nanoparticles in hyperthermia
New method that enhances the performance of iron oxide nanoparticles (IONPs), facilitating the implementation of magnetic hyperthermia (MH) therapies
New cancer treatments tend to be more selective and less toxic than current therapies. Among them, magnetic hyperthermia (MH) is a promising alternative. This is due to the higher sensitivity of tumour cells to high temperatures.
Iron-based oxide nanoparticles (IONPs) are promising candidates as heat mediators for MH, however, mass-produced IONPs often exhibit poor magnetic properties.
We have developed a new process that increase the magnetic properties of IONPs. It can be applied to any IONPs, no matter the production method used. As the process preserves size and surface functionality, it doesnt't affect biocompatibility, thus reducing the regulation roadmap for the application of the modified IONPs in MH, if they are already approved by FDA or EMA for other applications.